Addiction: Prolonged usage of codeine causes Actual physical and psychological dependence [eight]. After a while, The body might have more in the medication to operate Typically, making it not easy to Stop with out assistance.
NSAIDs may cause damage to kidneys. This really is almost certainly when taken for extended periods of time and in more mature men and women, notably Individuals whose kidneys have already got some destruction.
An individual could apply topical steroids to the skin that can help control inflammatory pores and skin ailments. On the other hand, people today can also knowledge topical steroid…
This will take place even if you take Promethazine Hydrochloride and Codeine Phosphate Oral Solution particularly as prescribed by your Health care provider. Your hazard of dependancy, abuse, and misuse is greater if you or a relative incorporates a background of drug or alcohol abuse or habit, or psychological health problems.
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Constipation: Codeine slows down the digestive technique, resulting in constipation. This can become uncomfortable if Stilpane is employed for lengthy intervals.
The concomitant utilization of Promethazine HCl and Codeine Phosphate Oral Option with all cytochrome P450 2D6 inhibitors (e.g., amiodarone, quinidine) may perhaps end in a rise in codeine plasma concentrations in addition to a reduce in Energetic metabolite morphine plasma concentration which could lead to an analgesic efficacy reduction or symptoms of opioid withdrawal.
People could illegally use anabolic steroids to boost muscle mass, overall performance, and endurance and also to shorten Restoration time in between exercise routines.
Lifestyle-threatening breathing problems (respiratory depression). Promethazine Hydrochloride and Codeine Phosphate Oral Remedy may cause respiratory issues (respiratory melancholy) that will occur Anytime all through therapy and can lead to Loss of life. Your danger of respiratory issues is greatest whenever you first get started using Promethazine Hydrochloride and Codeine Phosphate Oral Remedy, are taking other medicines that might cause breathing problems, have particular lung challenges, are aged or have certain other health problems.